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Source document· February 25, 2026

TransMedics outlines 20–25% 2026 revenue growth target while advancing OCS programs and European expansion

View original at seekingalpha.com
TransMedics outlines 20–25% 2026 revenue growth target while advancing OCS programs and European expansion Earnings Call Insights: TransMedics Group, Inc…
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  • Company is laser-focused on ensuring successful execution of initiatives throughout 2026

    80% confidence
  • Almost 50% of incremental 2026 investment is driven by three transitory elements

    80% confidence
  • Total revenue for Q4 2025 was $160.8 million, representing approximately 32% growth year-over-year and approximately 12% sequential growth from Q3 2025

    80% confidence
  • Total revenue for Q4 2025 was $160.8 million, representing approximately 32% year-over-year growth and approximately 12% sequential growth

    80% confidence
  • OUS (outside U.S.) transplant revenue grew approximately 33% sequentially to $5 million in Q4 2025

    80% confidence
  • Gross margin for full year 2025 was 59.9%, up from 59.4% in 2024, reflecting logistics efficiencies and scale benefits

    80% confidence
  • Total revenue for Q4 2025 was $160.8 million, representing approximately 32% growth year-over-year and approximately 12% sequential growth from Q3 2025

    80% confidence
  • OCS Liver reached 36% of U.S. liver transplant volume in 2025, up from 26% in 2024

    80% confidence
  • Total revenue for Q4 was approximately $161 million with U.S. transplant revenue at approximately $155 million, up 33% year-over-year and 11% sequentially

    80% confidence
  • Liver share gains are pure TransMedics execution excellence

    80% confidence
  • TransMedics is laser-focused on ensuring successful execution of these initiatives throughout 2026

    80% confidence
  • OCS was responsible for 5,139 U.S. transplants in 2025, up from 3,735 in 2024

    80% confidence
  • Competitor in ENHANCE Part B trial (makers of styrofoam box) is refusing to randomize their technology against TransMedics

    80% confidence
  • OCS was responsible for 5,139 U.S. transplants in 2025, up from 3,735 in 2024

    80% confidence
  • Total revenue for Q4 2025 was $160.8 million, representing approximately 32% growth year-over-year and approximately 12% sequential growth from Q3 2025

    80% confidence
  • Upcoming registry publication will demonstrate unequivocal statistical superiority in the most important outcomes after liver transplantation

    80% confidence
  • TransMedics achieved its best operational performance to date despite external challenges earlier in the year designed to distract and disrupt sustained growth

    80% confidence
  • TransMedics achieved our best operational performance to date with these results achieved despite external challenges earlier in the year that were designed to distract and disrupt our sustained and transformational growth

    80% confidence
  • OCS Heart comprised 18% of heart transplants in 2025, up from 17% in 2024

    80% confidence
  • TransMedics is laser-focused on ensuring successful execution of 2026 initiatives

    80% confidence
  • TransMedics delivered an operating profit of approximately $21.3 million in Q4, representing approximately 13.2% of total revenue

    80% confidence
  • Most lung centers were waiting to see FDA approval to start launching into DENOVO program

    80% confidence
  • Almost 50% of incremental 2026 investment is driven by three transitory elements

    80% confidence
  • NOP Connect 2.0 is showing efficiency in management and billing, though in early stages

    80% confidence
  • U.S. transplant revenue grew approximately 11% sequentially to $155 million

    80% confidence
  • OCS was responsible for 5,139 U.S. transplants in 2025, up from 3,735 in 2024

    80% confidence
  • OCS Liver reached 36% of U.S. liver transplant volume, up from 26% in 2024, and OCS Heart comprised 18% of heart transplants, up from 17%

    80% confidence
  • By organ, liver contributed $127 million, heart $26 million and lung $2 million in Q4

    80% confidence
  • Operating margin expanded from 8.5% in 2024 to 18% in 2025

    80% confidence
  • TransMedics is not seeing competitive dynamics impacting ability to execute in 2026 and beyond

    80% confidence
What we know · the intelligence behind this page
Live from the substrate
What we're seeing
Q4 2026 Biotech Catalyst Window: ESMO Data, the Ivonescimab PDUFA and Small-Cap Delistings
Mid-October to November 2026 is a dense catalyst period for clinical-stage biotech. Positive late-stage readouts (ALOFT-IPF, TELIGAN, MIUDELLA, the duvakitug extension) and the ESMO 2026 presentations lead up to the FDA's 14 November PDUFA date for the ivonescimab BLA. At the opposite end of the market, Spago Nanomedical is moving to delist from Nasdaq First North, which shows how hard it is for micro-cap developers to fund themselves. Value is concentrating in companies with late-stage data and near-term regulatory outcomes.
Our read on the data ›
Signals we're tracking
EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
Patterns we're watching ›
Where sources disagree
Ford Motor Company
Both facts give cash for Ford Motor Company at the same point in time (2025-12-31; FY 2025 year-end and Q4 2025 year-end are the same date). Both are labelled USD, but the values are 23,356,000,000 and 23.356, which cannot both be true in USD. The two numbers agree once the second is read as billions (23.356 bn = 23,356,000,000), so the economic content is consistent and the conflict is a unit/scale error in the Q4 2025 record. The period is not the reason for the conflict: a Q4 and an FY figure at the same year-end date should match.
We flag conflicts openly ›
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